Leigh’s syndrome (LS) or subacute necrotizing encephalomyelopathy was first described by the neuropathologist Denis Leigh in a 7-month infant who had died of the disease, and on whom he performed an autopsy. It occurs quite rarely, in about 1 in 40,000 births, and may be due to either a mitochondrial DNA (mtDNA) or nuclear mutation. Two ethnic populations have a high incidence (1 in 2,000 to 1 in 2,500 births).
What is Leigh's Syndrome?
Dr Rohit Bhaskar May 11, 2022