Ring Vaccination May not be Effective against Monkeypox

NEW DELHI: Even as the health experts from around the globe have been stressing on the need to implement ring vaccination among the people at risk with monkeypox, a new study, not peer-reviewed yet, has claimed that the strategy may not be completely effective in curbing the current outbreak. 

Ring vaccination, which has been used successfully to contain smallpox and Ebola outbreaks, means to vaccinate a "ring" of people around the infected rather than vaccinating an entire population, ideally within four days of exposure. 



The study led by a team, including from Universite Paris Cite in France, showed that ring vaccination may not completely protect against infections. The findings were based on a third-generation smallpox vaccine recommended in France for individuals who had a high-risk contact with a PCR-confirmed Monkeypox patient. 

The study aimed to describe the outcomes of high-risk contacts receiving third-generation smallpox vaccine as an early post-exposure ring vaccination (EPRV) especially tolerance and potential breakthrough infections after the first dose. The team performed an observational analysis of all consecutive individuals vaccinated with the IMVANEX smallpox vaccine after a high-risk contact. 

It was defined as close skin-to-skin or mucosal contact and/or indirect contact on textile or surface and/or droplets exposure defined by a contact at less than 2 meters during at least 3 hours with a PCR-confirmed Monkeypox patient.

Between May 27 and July 13, 276 individuals received one dose of IMVANEX with a median delay of 11 days after exposure with a confirmed Monkeypox patient.

Mode of exposure was droplets for 240 patients (91 per cent), indirect contact for 189 (71 per cent) and unprotected sexual intercourse for 146 (54 per cent). Most of the patients were men (91 per cent) and men who have sex with men (88 per cent). The vaccine was well tolerated with no severe adverse event. (IANS)
Dr Rohit Bhaskar, Physio
Dr Rohit Bhaskar, Physio Dr. Rohit Bhaskar, Physio is Founder of Bhaskar Health and Physiotherapy and is also a consulting physiotherapist. He completed his Graduation in Physiotherapy from Uttar Pradesh University of Medical Sciences. His clinical interests are in Chest Physiotherapy, stroke rehab, parkinson’s and head injury rehab. Bhaskar Health is dedicated to readers, doctors, physiotherapists, nurses, paramedics, pharmacists and other healthcare professionals. Bhaskar Health audience is the reason I feel so passionate about this project, so thanks for reading and sharing Bhaskar Health.

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